TER (Bubeck)

The Tubular Extraction Rate (TER) estimation is based on Bubeck's single-sample method. A single blood sample is sufficient to determine the TER after the injection of [^99mTc]MAG3. However, in clinical routine, two different samples are usually taken to assess the reproducibility of the TER estimation.

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Patient

Weight

Height

Date of birth

BMI

–

kg/m²

Est. Body Surf. Area

–

m²

Injection

Seringe activity

MBq

Time of measurement

Time of injection

Seringe residual activity

MBq

Time of measurement

Blood samples

Sample 1 activity

cpm

Timepoint of Sample 1

Time of measurement

Sample 2 activity

cpm

Timepoint of Sample 2

Time of measurement

Well counter efficiency factor

cpm/kBq

Results

Tubular excretion rate

–

ml/min/1.73 m²

(–)

TER calculated from Sample 1

–

ml/min/1.73 m²

TER calculated from Sample 2

–

ml/min/1.73 m²

Age dependant expected value

–

ml/min/1.73 m²

70% of Age expected value

–

ml/min/1.73 m²

References

DuBois D, DuBois EF. A formula to estimate the approximate surface area if height and weight are known. Arch Int Med. 1916; 17 863-871.

Bubeck B. Renal clearance determination with one blood sample: improved accuracy and universal applicability by a new calculation principle. Semin Nucl Med. 1993; 23 73-86.